DNA Sensors


Project title: Single stranded DNA biorecognition for biomarkers of cancer and other diseases

Postgraduate researchers: Godfrey Fuku, Ayman Saeed, Lei Shi

Objective: Novel bioanalytical methodologies capable of detecting biomarkers of disease spanning small molecules, metal ions, enzymes and cancer related proteins.

Collaborators: Emmanuel Iwuoha, Priscilla Baker, University of the Western Cape, Capetown, South Africa, Mohammad Abbas, National Research Centre, Cairo, Egypt, Wanqin in, Nanjing University of Technology, Nanjing, China.

Funding: FP7 Marie Curie International Research staff Exchange “SMARTCANCERSENS”.

1. Lei Shi, Zhenyu Chu, Xueliang Dong, Wanqin Jin and Eithne Dempsey, ‘A highly oriented hybrid microarray modified electrode fabricated by a template-free method for ultrasensitive electrochemical DNA recognition’, Nanoscale 2013, 5, 10219.
2. A gallium telluride quantum dots bioelectrode system for human epidermal growth factor receptor-2 (Her2/neu) oncogene signalling, Xolile Fuku, Baljit Singh, Rachel F. Ajayi, Abongile N. Jijana, Priscilla Baker, Eithne Dempsey and Emmanuel Iwuoha Anal. Methods, 2015,7, 6114-6124.
3. Mohammed Nooredeen Abbas, Ayman Ali Saeed, Baljit Singh, Abdellatef A. Radowan and Eithne Dempsey, ‘Cysteine sensor based on Gold nanoparticles-Iron phthalocyanine modified graphite paste electrode’, Analytical Methods 2015,7, 2529-2536 .

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