Centre of Applied Science for Health

The Centre of Applied Science for Health was built in 2007 as a collaborative effort between biology and chemistry research groups at TU Dublin - Tallaght Campus, NUI Maynooth, the National Institute of Cellular Biotechnology at Dublin City University and Tallaght Hospital. 

It was funded under the Higher Education Authority - Programme for Research in Third Level Institutions (PRTLI) Cycle 4. The aims of the Centre are to create a connected system of research, innovation and commercial translation to bring research findings to clinical and commercial settings; enable and deliver upon a targeted program of research involving microbiology, cell biology, diagnostic sensors, and biomechanical engineering; actively create and seek out opportunities for effective engagement with industry in collaborative  applied research.

The Centre of Applied Science and Health has an excellent pedigree in carrying out research in areas such as Microbial Host Interactions; Bioengineering Technology; Biomedical Devices; Pharmaceutical & Materials Analysis; Antimicrobials; Sensors.  

There has been a concerted move, in recent years, towards research to support the industry and also towards more applied and commercial R&D. This has led to the establishment of a commercial wing MiCRA (Microsensors for Clinical Research and Analysis). 

MiCRA-Biodiagnostics is part of Enterprise Ireland’s Technology Gateway Network, which provides technology solutions and support to SME’s and specialises in the development of microsensors for the food, pharmaceutical, diagnostics, biotechnology, environmental, human and animal healthcare and agriculture sectors. The Centre can also provide a range of bio analytical, material and food characterisation, microbiological and food safety and chemical analytical services for the food, pharmaceutical and medical devices sectors. It has a track record in service provision for companies using NMR, GC-MS, LC-MS, SEM etc. It can offer bespoke and standard solutions to industry service requirements.

Academic Principal Investigators:
Maire Callaghan - Emma Caraher - Gordon Cooke - Maureen Walsh
Bernadette S. Creaven - Ed Carey - Fintan Kelleher - Denise A. Egan
Adrienne Fleming - Brian A. Murray - Shane Murphy - Tony Tansey   
Baljit Singh - Kieran Collins - Fiona McEvoy - Stephen Tiernan
Mary Deasy (also Centre Manager)          
3 Senior Scientists
34+ Postgraduate Researchers
2 Scientists – Biodiagnostics Area

A selection of collaborators which we have publications with is provided:
NUI Maynooth; Dublin Institute of Technology; University College Dublin; Dublin City University; University of Copenhagen; Sheffield University; Nanjing University of Technology; University of Pisa; University of the Western Cape; University of Seville; Birmingham University; Hungarian Academy of Sciences; Bulgarian Academy of Sciences; Claude Bernard University, Lyon; Liverpool John Moores University; Liverpool Hope University; St. Vincent‘s Hospital, Dublin; Tallaght Hospital, Dublin; Irish Centre of High-End Computing.
Companies that have joint research degree projects with Centre currently include Trinity Biotech; Novareus; Connexicon; Ipsen, Glanbia.

Selected Publications: 

  • Maeve Sullivan, Agnieszka Folytn-Arfa Kia, Mark Long, Maureen Walsh, Kevin Kavanagh, Siobhán McClean, Bernadette S. Creaven Polyhedron 67 (2014) 549–559
  • Muhammad Mujahid, Natasha Trendafilova, Agnieszka Foltyn Arfa-Kia, Georgina Rosair, Kevin Kavanagh, Michael Devereux, Maureen Walsh, Siobhán McClean, Bernadette S. Creaven, Ivelina Georgieva Journal of Inorganic Biochemistry 163 (2016) 53–67
  • Darren Crowe, Alan Nicholson, Adrienne Fleming, Ed Carey, Goar Sánchez-Sanz, Fintan Kelleher Bioorganic & Medicinal Chemistry 25 (2017) 4285–4296
  • Kim Manzor, Keith ó Proinsias, Fintan Kelleher Tetrahedron Letters 58 (2017) 2959–2963
  • Lopez-Cornejo; F.J. Ostos; J. A. Lebron; M. L. Moya; M. Deasy, Colloids and Surfaces B: Biointerfaces 2015, 127, 65-72 
  • Shane Murphy, Karl Bauer, Peter A. Sloan, James J. Lawton, Lin Tang, and Richard E. Palmer Applied Physics Express 8, 126601 (2015)
  • Tony Loughman, Baljit Singh, Brian Seddon, Philip Noone and Padmanabhan Santhosh Analyst, 2017,142, 2725-2734

Research Visits/Visitors:
Resident Companies that rent space on the top floor of the Centre: Connexicon – Surgical Glue area; Vornia – polymers for medical devices; BBB Technologies – industrial grade polymers; Chinnery Spirits – Food & Beverage area.

Research Visitors to that have come to work at the Centre include researchers from:
National - UCD, RCSI, NUI Maynooth, Tallaght Hospital 
International – IMBiG NASU, Ukraine; Montpelier University, France; Nanjing University of Technology, China, Universade Nova de Lisboa, Portugal; University of California, Berkley, USA; Higher School of Science and Technology of Hammam Sousse, Tunisia; University of Western Cape, South Africa; University of Leipzig, Germany; Ohio State University, USA; Institute of Biostructures and Bioimaging, National Research Council, Naples, Italy; National Research Centre, Cairo, Egypt; University of Wroclaw, Poland.

Commercialisation outputs:

  • Product development support for Bimeda (two commercial products)
  • NDA with Connexion, Surgical Glue Company for a potential product using compounds synthesised within the MDS group
  • Three Invention Disclosures from SFI project.

Other Information: 
Extensive experience as Journal Reviewers across a wide range of publishers
Management Committee level involvement in EU COST Actions
Coordination of the National Pharmaceutical Education Centre – responsible for of the industry relationships involved on the Education and training side of the Department of Science
Founding and administration of AMR Ireland (Anti-microbial Resistance Ireland)

  • Synergy Centre at ITT Dublin
  • QQI Brand Logo
  • Member of the Technological University for Dublin Alliance
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